Use implicit differentiation where LaTeX:  \displaystyle y is a function of LaTeX:  \displaystyle x to find the derivative of LaTeX:  \displaystyle 9 x^{3} y^{3} + \sin{\left(x^{3} \right)} \cos{\left(y^{3} \right)}=-10

Taking the derivative of both sides using implicit differentiation gives: LaTeX:   27 x^{3} y^{2} y' + 27 x^{2} y^{3} + 3 x^{2} \cos{\left(x^{3} \right)} \cos{\left(y^{3} \right)} - 3 y^{2} y' \sin{\left(x^{3} \right)} \sin{\left(y^{3} \right)} = 0  Solving for LaTeX:  \displaystyle y' gives LaTeX:  \displaystyle y' = - \frac{x^{2} \left(9 y^{3} + \cos{\left(x^{3} \right)} \cos{\left(y^{3} \right)}\right)}{y^{2} \left(9 x^{3} - \sin{\left(x^{3} \right)} \sin{\left(y^{3} \right)}\right)}