Use implicit differentiation where LaTeX:  \displaystyle y is a function of LaTeX:  \displaystyle x to find the derivative of LaTeX:  \displaystyle - 2 y^{2} \cos{\left(x \right)} + 9 \sin{\left(x^{2} \right)} \sin{\left(y^{2} \right)}=-27

Taking the derivative of both sides using implicit differentiation gives: LaTeX:   18 x \sin{\left(y^{2} \right)} \cos{\left(x^{2} \right)} + 2 y^{2} \sin{\left(x \right)} + 18 y y' \sin{\left(x^{2} \right)} \cos{\left(y^{2} \right)} - 4 y y' \cos{\left(x \right)} = 0  Solving for LaTeX:  \displaystyle y' gives LaTeX:  \displaystyle y' = \frac{9 x \sin{\left(y^{2} \right)} \cos{\left(x^{2} \right)} + y^{2} \sin{\left(x \right)}}{y \left(- 9 \sin{\left(x^{2} \right)} \cos{\left(y^{2} \right)} + 2 \cos{\left(x \right)}\right)}