Use implicit differentiation where LaTeX:  \displaystyle y is a function of LaTeX:  \displaystyle x to find the derivative of LaTeX:  \displaystyle 3 x \sqrt{y} - 8 e^{x^{2}} \cos{\left(y \right)}=-46

Taking the derivative of both sides using implicit differentiation gives: LaTeX:   - 16 x e^{x^{2}} \cos{\left(y \right)} + \frac{3 x y'}{2 \sqrt{y}} + 3 \sqrt{y} + 8 y' e^{x^{2}} \sin{\left(y \right)} = 0  Solving for LaTeX:  \displaystyle y' gives LaTeX:  \displaystyle y' = \frac{2 \left(16 x \sqrt{y} e^{x^{2}} \cos{\left(y \right)} - 3 y\right)}{3 x + 16 \sqrt{y} e^{x^{2}} \sin{\left(y \right)}}